Development of topical mosquito repellent emulgels containing Zanthoxylum limonella essential oils

Authors

Walaisiri Muangsiri
Thi Thi San
Pornpen Werawatganone

Abstract

Emulgels containing 18% w/w Zanthoxylum limonella Alston essential oils were developed as a mosquito repellent. The physical and chemical stabilities and in vivo efficacy of the product were evaluated. Physical stability was tested at 30°C, 75% RH, and 40°C, 75% RH for 3 months or using six heating–cooling cycles. The chemical stability of d-limonene and vanillin contents was analyzed using a gas chromatograph equipped with a flame ionization detector. In vivo mosquito repellency test was performed using the human-bait technique. The product, which contains 11.4% w/w d-limonene and 5% w/w vanillin, was homogeneous and off-white with sweet and mild citrus odor. It was physically and chemically stable up to 2.5 months. In the presence of 5% w/w vanillin, the product showed up to 3 h mosquito repellent efficacy against Aedes aegypti.

DOI

10.56808/3027-7922.2819

Recommended Citation

Muangsiri, Walaisiri; San, Thi Thi; and Werawatganone, Pornpen (2023) "Development of topical mosquito repellent emulgels containing Zanthoxylum limonella essential oils," The Thai Journal of Pharmaceutical Sciences: Vol. 47: Iss. 2, Article 7.
DOI: https://doi.org/10.56808/3027-7922.2819
Available at: https://digital.car.chula.ac.th/tjps/vol47/iss2/7