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The Thai Journal of Pharmaceutical Sciences

Abstract

Vitamin E, which belongs to a class of lipid-soluble vitamins, is considered one of the most essential nutrients for the well-being of humans but can solely be obtained through diet. This Vitamin E group includes all the tocol and tocotrienol derivatives which are reported to exhibit diverse biological activities as evident from a literature survey. However, the current pharmacotherapies mainly target the different oxidation processes of the body that have been linked to numerous disease conditions such as cancer, arthritis, atherosclerosis, aging, and others. On that note, Vitamin E has multiple important roles within the body and recent studies indicate that γ-tocopherol, δ-tocopherol and γ-tocotrienol have unique antioxidant and anti-inflammatory properties which are superior to α-tocopherol in the prevention of chronic diseases. In addition, Vitamin E scavenges peroxyl radicals and inhibits pro-inflammatory signaling which may be useful in the treatment of inflammation-related disorders. In this review, we have discussed different medicinal functions of Vitamin E in various human diseases based on available literature.

DOI

10.56808/3027-7922.2814

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