The Thai Journal of Pharmaceutical Sciences
Abstract
Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM), popularly known as “Kwao Krua,” is a medicinal plant that has been used for centuries in Thailand. Phytochemical studies indicated the presence of several bioactive molecules such as miroestrol, deoxymiroestrol, puerarin, daidzein, daidzin, genistin, genistein, and kwakhurin. The pharmacological evaluation of PM indicated strong estrogenic, anti-osteoporosis effects, anti-aging and antioxidant activities, as well as the ability to relieve other climacteric-related symptoms. There is conflicting evidence on the safety and toxicity of PM. The active ingredients in PM make it an ideal candidate for large-scale pharmaceutical exploitation as a cosmeceutical. Further studies are needed to evaluate its safety and toxicity in humans.
Publisher
Faculty of Pharmaceutical Sciences, Chulalongkorn University
First Page
1
Last Page
10
Recommended Citation
Rani, Dolly; Kobtrakul, Khwanlada; and Vimolmangkang, Sornkanok
(2022)
"Pueraria candollei var. mirifica: A
precious source of pharmaceuticals and
cosmeceuticals,"
The Thai Journal of Pharmaceutical Sciences: Vol. 46:
Iss.
1, Article 1.
Available at:
https://digital.car.chula.ac.th/tjps/vol46/iss1/1