The Thai Journal of Pharmaceutical Sciences
Abstract
Introduction: Chitosan, a biopolymer with 97% degree of deacetylation, was used herein, to synthesize an amino sugar anionic surfactant of varied alkyl chain length, using a microwave-assisted synthesis. We were also examined their properties in aqueous form. Objectives: The objectives of the study were to increase the surface activity and water solubility of chitosan derivatives. Materials and Methods: Structural features and crystallinity were confirmed using Fourier transform infrared, ¹H-nuclear magnetic resonance, and X-ray diffraction. The chitosan by itself was found to have weak surface-active properties since it has no hydrophobic segment. Results: The microwave-assisted synthesized sugar amino-based anionic surfactant, synthesis of (2-hydroxyl-3-butoxyl) propyl-succinyl-chitosan-succinyl chitosan was found to have excellent surface-active and detergency properties. The aggregation behavior of amino sugar anionic surfactant was characterized by surface tension, which indicated that it had good surface activity. Conclusion: We believe that good surface activities of synthesized water-soluble surfactants can be used in the formulations of face wash, body wash, liquid detergents, more applications in pharmaceutical, medicine and food industry, etc.
DOI
10.56808/3027-7922.2527
First Page
461
Last Page
469
Recommended Citation
Singh, P. S.; Mali, Suraj N.; Sangale, N. R.; and Pratap, Amit P.
(2021)
"Synthesis of (2-hydroxyl-3-butoxyl) propyl-succinyl-chitosan – An amino sugar anionic surfactant under microwave irradiation and its application,"
The Thai Journal of Pharmaceutical Sciences: Vol. 45:
Iss.
6, Article 4.
DOI: https://doi.org/10.56808/3027-7922.2527
Available at:
https://digital.car.chula.ac.th/tjps/vol45/iss6/4
