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The Thai Journal of Pharmaceutical Sciences

Abstract

Background: Along with a widespread application of cabbage as a food and fodder crop, it also possesses therapeutic properties. In traditional medicine, this plant is used in gastritis and gastric ulcer, colitis, diabetes, inflammations of upper airways, musculoskeletal system, disorders of cardiovascular system, and skin. Materials and Method: Using the method of gas chromatography, the component composition of cabbage leaves of Yaroslavna and Bilosnizhka cultivars was studied. Testing control strains of microorganisms were used for the determination of the antimicrobial activity of chloroform, ethyl acetate, and 96% ethanol extracts from cabbage cultivars leaves. Result: The general amount of volatile compounds in the studied plant material types was almost equal. Allyl isothiocyanate, dihydropseudoionone, and ar-turmerone were chosen as marker compounds for cabbage leaves of Yaroslavna cultivar, while nerolidol and 3,5-di-tret-butyl-4-hydroxybenzaldehyde were chosen for cabbage leaves of Bilosnizhka cultivar. Testing control strains of Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris, and Candida albicans were sensitive to all tested extracts from cabbage leaves of Yaroslavna and Bilosnizhka cultivars. Conclusion: The results provide the reason for the development of new antibacterial drugs based on cabbage leaves.

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

264

Last Page

272

Included in

Pharmacology Commons

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