Association of N-acetyltransferase 2 (NAT2) polymorphisms and elevated liver enzymes of Myanmar tuberculosis patients in Thailand

Authors

Khin Sandi Thaw
Chanchira Choppradit
Pornpimol Kijsanayotin
Ratchanee Rodsiri

Abstract

Isoniazid (INH) and its toxic metabolites are the major cause of anti-tuberculosis (TB) druginduced liver injury (AT-DILI). N-acetyltransferase 2 (NAT2) is involved in many metabolic pathways of INH. Previous studies demonstrated the association of NAT2 .

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

210

Last Page

215

Recommended Citation

Thaw, Khin Sandi; Choppradit, Chanchira; Kijsanayotin, Pornpimol; and Rodsiri, Ratchanee (2020) "Association of N-acetyltransferase 2 (NAT2) polymorphisms and elevated liver enzymes of Myanmar tuberculosis patients in Thailand," The Thai Journal of Pharmaceutical Sciences: Vol. 44: Iss. 4, Article 1.
Available at: https://digital.car.chula.ac.th/tjps/vol44/iss4/1