Synthesis and evaluation of PI3Kγ enzyme inhibitory activity of Novel (1H-pyrazol-4-yl)methanamine

Authors

Sukumar Bepary
In Kwon Youn
Hee-Jong Lim
Ge Hyeong Lee

Abstract

A series of (1H-pyrazol-4-yl)methanamines have been synthesized and then were evaluated for the PI3Kγ enzyme inhibitory potential. Minor modification of the initially synthesized molecules offered significant improvement of the inhibitory potential from...

DOI

10.56808/3027-7922.1927

First Page

82

Last Page

86

Recommended Citation

Bepary, Sukumar; Youn, In Kwon; Lim, Hee-Jong; and Lee, Ge Hyeong (2016) "Synthesis and evaluation of PI3Kγ enzyme inhibitory activity of Novel (1H-pyrazol-4-yl)methanamine," The Thai Journal of Pharmaceutical Sciences: Vol. 40: Iss. 2, Article 3.
DOI: https://doi.org/10.56808/3027-7922.1927
Available at: https://digital.car.chula.ac.th/tjps/vol40/iss2/3