In silico docking and pharmacophoric analysis of 3-indolyl pyridine derivatives toward cyclooxygenase-2

Authors

Sukumar Bepary
Ge Hyeong Lee
Hee Jong Lim
In Kwon Youn

Abstract

A series of 3-indolyl pyridine derivatives having anti-inflammatory activities were docked into the indomethacin binding pocket of cyclooxygenase-2 enzyme. In this in silico study, the possible orientations of the molecules in the binding site of the rec...

DOI

10.56808/3027-7922.1955

First Page

35

Last Page

40

Recommended Citation

Bepary, Sukumar; Lee, Ge Hyeong; Lim, Hee Jong; and Youn, In Kwon (2015) "In silico docking and pharmacophoric analysis of 3-indolyl pyridine derivatives toward cyclooxygenase-2," The Thai Journal of Pharmaceutical Sciences: Vol. 39: Iss. 2, Article 1.
DOI: https://doi.org/10.56808/3027-7922.1955
Available at: https://digital.car.chula.ac.th/tjps/vol39/iss2/1