In silico docking and pharmacophoric analysis of 3-indolyl pyridine derivatives toward cyclooxygenase-2

Authors

Sukumar Bepary
Ge Hyeong Lee
Hee Jong Lim
In Kwon Youn

Abstract

A series of 3-indolyl pyridine derivatives having anti-inflammatory activities were docked into the indomethacin binding pocket of cyclooxygenase-2 enzyme. In this in silico study, the possible orientations of the molecules in the binding site of the rec...

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

35

Last Page

40

Recommended Citation

Bepary, Sukumar; Lee, Ge Hyeong; Lim, Hee Jong; and Youn, In Kwon (2015) "In silico docking and pharmacophoric analysis of 3-indolyl pyridine derivatives toward cyclooxygenase-2," The Thai Journal of Pharmaceutical Sciences: Vol. 39: Iss. 2, Article 1.
Available at: https://digital.car.chula.ac.th/tjps/vol39/iss2/1