Development and validation of RP-HPLC method for analysis and stability study of 8-carboxyphenyl-2'-deoxyguanosine and 8-bromo-2'-deoxyguanosine

Authors

Kulwadee Sawatpaiboontawee
Panutsaya Sermthaveesub
Panuwat Sangsirimongkolying
Patratorn Kunakorntham
Sudarat Thongborriboon
Bodin Tuesuwan
Vorasit Vongsutilers

Abstract

Modifications on C8 position of purine base have been studied for their effects on B-DNA to Z-DNA conversion. The 8-bromo and 8-carboxyphenyl adduct are among the most potent Z-DNA facil tators and hence arc aimed to be utilized for Z-DNA based probe lor...

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

176

Last Page

181

Recommended Citation

Sawatpaiboontawee, Kulwadee; Sermthaveesub, Panutsaya; Sangsirimongkolying, Panuwat; Kunakorntham, Patratorn; Thongborriboon, Sudarat; Tuesuwan, Bodin; and Vongsutilers, Vorasit (2014) "Development and validation of RP-HPLC method for analysis and stability study of 8-carboxyphenyl-2'-deoxyguanosine and 8-bromo-2'-deoxyguanosine," The Thai Journal of Pharmaceutical Sciences: Vol. 38: Iss. 4, Article 4.
Available at: https://digital.car.chula.ac.th/tjps/vol38/iss4/4