Dissolution enhancement of dronedarone hydrochloride by complexation with ß-CD and HP ß-CD: dissolution and physicochemical characterization

Authors

Anjan Kumar Mahapatra
Supriya Samoju
Ruchita Kumari Patra
Padala Narasimha Murthy

Abstract

The study was aimed to improve solubility or dissolution characteristics of dronedarone hydrochloride by preparing its inclusion complexes (ICs) with ß-cyclodextrin (ß-CD) and hydroxypropyl ß-cyclodextrin (HP ß-CD). The phase solubility behavior of d...

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

139

Last Page

148

Recommended Citation

Mahapatra, Anjan Kumar; Samoju, Supriya; Patra, Ruchita Kumari; and Murthy, Padala Narasimha (2014) "Dissolution enhancement of dronedarone hydrochloride by complexation with ß-CD and HP ß-CD: dissolution and physicochemical characterization," The Thai Journal of Pharmaceutical Sciences: Vol. 38: Iss. 3, Article 4.
Available at: https://digital.car.chula.ac.th/tjps/vol38/iss3/4