Protective effect of deferiprone on 7-ketocholesterol formation in hemin-induced LDL oxidation

Authors

Usa Suwannasual
Thitima Pengsuparp
Rataya Luechapudiporn

Abstract

Hemin (iron (III)-protoporphyrin IX) is found that it is elevated in the plasma of thalassemic patients and is a possible cause of oxidative stress-promoting atherosclerosis. Deferiprone (L1), an iron chelator, can prevent free radical formation catalyze...

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

14

Last Page

20

Recommended Citation

Suwannasual, Usa; Pengsuparp, Thitima; and Luechapudiporn, Rataya (2014) "Protective effect of deferiprone on 7-ketocholesterol formation in hemin-induced LDL oxidation," The Thai Journal of Pharmaceutical Sciences: Vol. 38: Iss. 1, Article 3.
Available at: https://digital.car.chula.ac.th/tjps/vol38/iss1/3