Thrombolytic activity of some spices and plants available in Bangladesh

Authors

Md. Rakib AI-Manun
Nabiha Amrin
Jahura Begum
Md. Abdul Mazid

Abstract

Thrombolytic activities of some plants, namely Tamarindus indica (Fabaceae), Flemingia congesta (Fabaceae), Lawsonia inermis (Lythraceae), Mesua nagassarium (Clusiaceae, and spices, namely Coriandrum sativum (Apiaceae), Curcuma longa (Zingiberaceae), Cinnamomum tamala (Lauraceae), Nigella sativa (Ranunculaceae), Eugenia aromaticum (Myrtaceae), available in Bangladesh, were evaluated using an in vitro model. The thrombolytic activity in terms of percentage of weight loss of in vitro formed clots were found as C. sativum 43.25 ± 7.18%, C. longa 53.32 ± 4.96%, C. tamala 22.10 ± 3.18%, N. sativa 28.49 ± 3.72%, E. aromaticum 32.18 ± 3.10%, T. indica 28.91 ± 2.29%, F. congesta 35.27 ± 7.35%, L. inermis 62.40 ± 5.04%, M. nagassarium bark 39.54 ± 7.15% and M. nagassarium leaf 46.75 ± 3.97% with reference to the negative control distilled water 8.37 ± 1.18% and positive control streptokinase 84.63 ± 1.03%. Through our study, it was found that L. inermis and C. longa possess thrombolytic property that could lyse blood clots in vitro.

DOI

10.56808/3027-7922.3316

First Page

72

Last Page

77

Recommended Citation

AI-Manun, Md. Rakib; Amrin, Nabiha; Begum, Jahura; and Mazid, Md. Abdul (2012) "Thrombolytic activity of some spices and plants available in Bangladesh," The Thai Journal of Pharmaceutical Sciences: Vol. 36: Iss. 2, Article 4.
DOI: https://doi.org/10.56808/3027-7922.3316
Available at: https://digital.car.chula.ac.th/tjps/vol36/iss2/4