The Thai Journal of Pharmaceutical Sciences
Abstract
Each topical indomethacin solution formulated was composed of ethanol, propylene glycol, a surfactant and water. The surfactants studied were polysorbate 80, pluronic F127 and pluronic F68. Predicted shelf lives at an average laboratory room temperature (33 ℃) of the formulations containing 5% polysorbate 80, 5% pluronic F127 and 5% pluronic F68 were 8.23, 7.43 and 5.06 years, respectively. From a statistical point of view, first order rate constants predicted by the Arrhenius equation were not different from those actually obtained at ambient temperature.
DOI
10.56808/3027-7922.3303
First Page
27
Last Page
39
Recommended Citation
Vayumhasuwan, Panida and Tharasawaeng, Saranya
(1995)
"Development of a stable topical indomethacin solution,"
The Thai Journal of Pharmaceutical Sciences: Vol. 19:
Iss.
1, Article 3.
DOI: https://doi.org/10.56808/3027-7922.3303
Available at:
https://digital.car.chula.ac.th/tjps/vol19/iss1/3