•  
  •  
 
Chulalongkorn Medical Journal

Abstract

Objective: To determine cut-off values for superior mediastinal width and the mediastinal width-to-thoracic cage ratio from chest radiographs for the early detection of unrecognized thoracic aortic diseases. Additionally, this study aims to enhance diagnostic strategies for identifying aortic abnormalities.

Materials and Methods: This retrospective analysis included 152 subjects who underwent both computed tomography angiography (CTA) of the thoracic aorta and chest radiograph between April 2007 and January 2021. Superior mediastinal width was measured at 3 levels on chest radiographs. Thoracic CTA findings were categorized into normal and abnormal groups, the latter comprising aortic dissection, intramural hematoma, penetrating atherosclerotic ulcer, and aneurysm. Cut-off values for superior mediastinal width and the mediastinal width-to-thoracic cage ratio were calculated using receiver operating characteristic (ROC) curve analysis.

Results: The optimal cut-off values were a mediastinal width ≥ 8.4 cm at the aortic knob level (ROC 77.3, 95% CI: 69.8-84.9, P

Conclusion: The established superior mediastinal width and ratio cut-off values from chest radiographs can help clinicians identify patients at risk for silent thoracic aortic disease, prompting further CTA evaluation that can prevent fatal outcomes and improve patient’s quality of life.

DOI

10.56808/2673-060X.5693

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.