Abstract
Renal osseous metaplasia is a rare condition in a native kidney with end stage renal disease showing mature bone with marrow elements in a background of chronic pyelonephritis. Although the pathogenesis is unknow, chronic ischemia and inflammation seems to be a trigger factor for the same. Osseous metaplasia has been reported in renal allograft specimen, but in this case report we present a histologically rare finding of osseous metaplasia in a native kidney.
Key words - Osseous metaplasia, native kidney, marrow elements
DOI
10.56808/2673-060X.5620
First Page
Type of Manuscript: Case report with review of literature Title: Bony affair – A rare case of osseous metaplasia a native non functioning kidney Authors: First author: Dr.Arthi.M, M.D., Pathology Assistant Professor, Dept of Pathology, Sri Ramachandra Medical College and Research Institute. Mail ID- arthiarun@sriramacahndra.edu.in Ph – 9380223344 Corresponding author: Dr.Leena D Joseph, M.D., Pathology Head and Professor, Dept of Pathology, Sri Ramachandra Medical College and Research Institute. Mail: leenadennisj@sriramachandra.edu.in Dr.Velmurugan.P, Mch., Urology Professor, Department of Urology, Sri Ramachandra Medical College and Research Institute. Mail: velumsdoc@rediffmail.com Dr.Meryl Saji Kottarathil M.D., Pathology Junior Resident, Dept of Pathology, Sri Ramachandra Medical College and Research Institute. Mail ID – meryl.saji@gmail.com
Last Page
References 1. Tefera AT, Ahmed MM, Tareke DG, Adem RY. A very rare case of bone metaplasia of renal cyst: A case report. International Journal of Surgery Case Reports. 2024 Sep 1;122:110083. 2. Tousignant K, Phan V, Clermont MJ, Metellus K, Perreault G, Sartelet H. Bone metaplasia associated with chronic allograft nephropathy. Kidney international. 2006 Aug 1;70(3):407. 3. Ozkanli S, Yildirim A, Zemheri E, Keskin SK, Basok EK. Osseous metaplasia and bone marrow elements in a case of renal cell carcinoma. Case Reports in Urology. 2012;2012(1):649257. 4. Azhir A, Riopel J, Solez K, Grynoch R, Sis B. Osseous and myeloid metaplasia in a failed renal allograft. Kidney international. 2007 Apr 2;71(8):829-30. 5. Makhoba AM, du Toit-Prinsloo L. Osseus metaplasia in chronic renal allograft rejection. African Journal of Nephrology. 2017 Jun 21;20(1):45-7.
Recommended Citation
M, Arthi Dr; Joseph, Leena Dennis Dr; P, Velmurugan Dr; and Kottarathil, Meryl Saji Dr
(2025)
"Bony Affair – A Rare Case of Osseous Metaplasia in a Native Non Functioning Kidney,"
Chulalongkorn Medical Journal: Vol. 69:
Iss.
6, Article 6.
DOI: https://doi.org/10.56808/2673-060X.5620
Available at:
https://digital.car.chula.ac.th/clmjournal/vol69/iss6/6
Fig.1 – H&E 200X showing thyroidisation of tubules and interstitial inflammatory infiltrate.
40X - marrow elements.JPG (2519 kB)
Fig.2 – H&E 400X showing fatty marrow elements along with megakaryocytes.