Dengue at Photharam Hospital: One among ten clinical trial sites of the world's first dengue vaccine
Abstract
Background: Dengue, a viral disease transmitted by vectors, is widespread worldwide, impacting more than 120 nations. In 2019, a concerning 5.2 million dengue cases were reported, with Asia bearing 70% of the global burden. Half of the global population faces the risk of dengue.
Objectives: The goal of this research was to illustrate the epidemiological pattern of dengue patients admitted to Photharam Hospital in Ratchaburi province, Thailand, one of the ten clinical trial sites for the world's first dengue vaccine.
Methods: Data from dengue patients admitted to Photharam Hospital, a provincial healthcare center in Ratchaburi province, Thailand, covering the period from January 2014 to December 2022, were examined. Diagnosis complied with the clinical and laboratory criteria outlined by the World Health Organization in 1997.
Results: During the study period, 2273 dengue patients were admitted to Photharam Hospital. Patients spanned all age groups, with a higher incidence among adults, and no gender differences were observed. The disease occurred year-round, peaking during the rainy season from June to September. All degrees of dengue severity were observed across age groups, with an overall case fatality rate of 0.22%.
Conclusion: Our findings reveal changing epidemiology at Photharam Hospital, particularly in the age group distribution of dengue patients. These insights are crucial for developing strategies to prevent and control dengue epidemics. The epidemiological trends observed may have relevance to regions globally experiencing similar changes in population demographics.
DOI
10.56808/2673-060X.5419
Recommended Citation
Tiawilai, Anongrat; Tiawilai, Chawin; Tiawilai, Thawat; Srisawat, Nattachai; Limothai, Umaporn; Tantawichien, Terapong; and Thisyakorn, Usa
(2025)
"Dengue at Photharam Hospital: One among ten clinical trial sites of the world's first dengue vaccine,"
Chulalongkorn Medical Journal: Vol. 69:
Iss.
4, Article 2.
DOI: https://doi.org/10.56808/2673-060X.5419
Available at:
https://digital.car.chula.ac.th/clmjournal/vol69/iss4/2
Fig 1. Age distribution of dengue patients in Photharam Hospital, Thailand between 2014 and 2022
Fig 2.tiff (1553 kB)
Fig 2. Seasonal distribution of dengue patients in Photharam Hospital, Thailand between 2014 and 2022
Fig3.tiff (831 kB)
Fig 3. Severity of dengue patients by age group in Photharam Hospital, Thailand between 2014 and 2022
Table 1.docx (14 kB)
Table 1. Clinical data of 5 dead cases