Abstract
The COVID-19 vaccine has the potential to decrease hospitalizations and fatalities, even when different vaccine types are administered. Towards the end of 2021, during the ongoing COVID-19 pandemic, there were guidelines suggesting the administration of booster shots following the completion of the primary vaccine series. Consequently, this study aims to investigate the efficacy of COVID-19 booster vaccinations and the timing between booster shots in terms of preventing fatalities among COVID-19-infected patients receiving care at Si Sa Ket Hospital
A retrospective cohort study was conducted on individuals aged 18 and above who were hospitalized with COVID-19 infection at Si Sa Ket Hospital from January 1, 2022, to December 31, 2022. Data analysis was performed using both descriptive statistics and multiple regression analysis techniques.
The study included a total of 1,853 patients, with 1,050 of them being female (56.66%). The average age was 53.80±20.43 years. Among them, 330 patients (17.81%) passed away. When stratified according to survival based on vaccination history, the survival rates for those who did not receive any vaccination, received an incomplete series and completed the full series were 68.52%, 75.88%, and 85.61%, respectively. In the groups that received one booster shot and two booster shots, the survival rates were 88.56% and 96.15%, respectively. Regarding the time interval between receiving booster shots, when comparing those vaccinated within 3 months, 3-6 months, and more than 6 months, there were no statistically significant differences found.
Conclusion and recommendations: COVID-19 booster vaccinations have proven their efficacy in preventing fatalities among hospitalized COVID-19-infected patients, even after a single booster dose. Additionally, receiving a booster shot at an interval of more than 6 months can still manage to reduce fatalities compared to booster shots administered within 3 months, with no statistical difference observed.
DOI
10.56808/2673-060X.5388
Recommended Citation
Tem-eiam, Nidhikul
()
"The impact of COVID-19 booster vaccination on reducing mortality in patients hospitalized with COVID-19 at Sisaket Hospital,"
Chulalongkorn Medical Journal: Vol. 68:
Iss.
3, Article 5.
DOI: https://doi.org/10.56808/2673-060X.5388
Available at:
https://digital.car.chula.ac.th/clmjournal/vol68/iss3/5