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Chulalongkorn Medical Journal

Abstract

Background: The common clinical manifestations of neurocysticercosis (NCC) was determined by several important factors. There is no previous study showing a correlation between difference stage of NCC and clinical presentation. The propose of this study was to determine correlation between different stages of NCC and its clinical presentation. Methods: A retrospective descriptive study was performed using medical records and picture archiving and communication system from October 14, 2004 to October 18, 2019 in patients who definite diagnosed NCC from computerized tomography (CT) or magnetic resonance imaging (MRI) of brain. Neuroimaging was reviewed by two observers. The correlation between stage of NCC and clinical presentation was analyzed independently using Chi-square test and regression analysis. Results: Statistical analysis was performed on 28 patients; Vesicular stage was seen in 8 (28.6%) patients, colloidal vesicular stage was seen in 8 (28.6%) patients, granular nodular stage was seen in 10 (35.7%) patients, nodular calcified stage was seen in 11 (39.3%) patients. Most patients, the lesions were located in the cerebral hemisphere 25 (89.3%) patients. Perileisonal edema was seen in 16 (57.1%) patients. There was no correlation between different stage of NCC and clinical presentation. But the location of NCC on cerebral hemisphere, perilesional edema and onset of clinical presentation were significant on seizure group (P = 0.026, P = 0.010 and P = 0.018, respectively). Location in cerebral hemisphere, perileisonal edema and onset of clinical presentation were imaging and clinical variables that was associated with seizure group on univariate analysis regression. However, on multivariate binary logistic regression, location in cerebral hemisphere, perilesional edema and onset of clinical presentation were not the factor to be independently associated with seizure group. Conclusion: There is no correlation between different stages of NCC and its clinical presentations.

DOI

10.58837/CHULA.CMJ.66.3.13

First Page

353

Last Page

363

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