Chulalongkorn Medical Journal


Background: Currently, there has been limited effective and practical instruments for screening post-stroke depression (PSD) in Thailand. In 2014, Post-Stroke Depression Scale (PSDS) has been testified to be a valid and reliable self-rated questionnaire for evaluating Chinese patients with PSD. Objective: This study proposed to validate the Thai version of PSDS (PSDS-T) in Thai patients with acute ischemic stroke. Methods: The PSDS was translated into Thai language (PSDS-T). The validity and reliability were tested in 145 acute ischemic stroke patients. Subjects were consecutively recruited to complete PSDS-T; they were clinically evaluated for PSD using DSM-5 diagnosis of adjustment disorder with depressed mood or depressive disorder due to another medical condition by psychiatrists as the gold standard. Cronbach α and point-biserial correlation were respectively used to examine internal reliability and concurrent validity. Then the receiver operating characteristic (ROC) curve was used to determine the cut off score for PSDS-T. The items of the PSDS-T were classified by average clustering analysis. Results: The Cronbach α of PSDS-T exhibited good reliability (0.780). The point-biserial correlation coefficient between total PSDS-T and the diagnosis of PSD was 0.688. The score of 8 was set to be a cut-off value by ROC analysis with the sensitivity of 0.933 and specificity of 0.908. Conclusion: PSDS-T is a valid and reliable screening tool for PSD in Thai patients with acute ischemic stroke.


Faculty of Medicine, Chulalongkorn University



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