Chulalongkorn Medical Journal


Peutz-Jeghers polyps are hamartomas of the small bowel which occur as part of the Peutz-Jeghers syndrome,a rare autosomal dominant condition characterized by gastrointestinal polyps and mucocutaneous melanoticpigmentation. We, hereby, report a case of a young female suffering from this syndrome who presented withhyperpigmentation of the lips and acute intestinal obstruction due to intussusception. An exploratory laparotomy was performed which revealed jejuno-jejunal and jejuno-ileal intussusceptions for which resection and anastomosis was done. There were multiple intraluminal polyps in the jejunum which upon histopathological examination, showed features of Peutz-Jeghers polyp. But, on postoperative day 11, we found the pigmentation on her lips disappeared, the patient behaved well in the postoperative period.


Faculty of Medicine, Chulalongkorn University

First Page


Last Page