Chulalongkorn Medical Journal


Objective : This study was conducted to investigate predictors of mortality after isolatedcoronary artery bypass grafting (CABG).Design : Retrospective studySetting : King Chulalongkorn Memorial Hospital.Methods : Retrospective single-institutional data on risk factors and mortality werecollected from 196 patients who underwent isolated CABG by the samegroup of surgeons from November 2007-October 2008. The relationshipbetween risk factors and outcome was assessed using univariate andmultivariate analyses.Results : The mean age of the patients (30.1% women and 69.9% men) was 61.1 +/-9 years. Hypertension was the most common comorbidity factor (82.7%),followed by diabetes mellitus, smoking habit, stroke, renal impairment, andchronic obstructive pulmonary disease. Postoperative atrial fibrillation andventricular tachycardia were the two most common complications (21.4%).The patients were followed up for 12 months. The operative mortality was11.7% (23/196) in the patients undergoing CABG. The univariate analysisidentified 14 preoperative and 8 postoperative risks which were significantlycorrelated with operative mortality. Stepwise multivariate analysis of ourperioperative risk revealed that the predictors of operative mortality weremale gender, length of hospital stay, preoperative intra-aortic balloon pump,duration of mechanical ventilatory support, postoperative neurologicalcomplications, and wound infection.Conclusion : We conclude that coronary artery bypass grafting surgery should be performedin carefully selected patients, and prevention of postoperative complicationsis mandatory to reduce mortality.


Faculty of Medicine, Chulalongkorn University

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