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Chulalongkorn Medical Journal

Abstract

Objective : This study was conducted to investigate predictors of mortality after isolatedcoronary artery bypass grafting (CABG).Design : Retrospective studySetting : King Chulalongkorn Memorial Hospital.Methods : Retrospective single-institutional data on risk factors and mortality werecollected from 196 patients who underwent isolated CABG by the samegroup of surgeons from November 2007-October 2008. The relationshipbetween risk factors and outcome was assessed using univariate andmultivariate analyses.Results : The mean age of the patients (30.1% women and 69.9% men) was 61.1 +/-9 years. Hypertension was the most common comorbidity factor (82.7%),followed by diabetes mellitus, smoking habit, stroke, renal impairment, andchronic obstructive pulmonary disease. Postoperative atrial fibrillation andventricular tachycardia were the two most common complications (21.4%).The patients were followed up for 12 months. The operative mortality was11.7% (23/196) in the patients undergoing CABG. The univariate analysisidentified 14 preoperative and 8 postoperative risks which were significantlycorrelated with operative mortality. Stepwise multivariate analysis of ourperioperative risk revealed that the predictors of operative mortality weremale gender, length of hospital stay, preoperative intra-aortic balloon pump,duration of mechanical ventilatory support, postoperative neurologicalcomplications, and wound infection.Conclusion : We conclude that coronary artery bypass grafting surgery should be performedin carefully selected patients, and prevention of postoperative complicationsis mandatory to reduce mortality.

Publisher

Faculty of Medicine, Chulalongkorn University

First Page

17

Last Page

36

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