Chulalongkorn Medical Journal


Decreased height velocity (HV), one of the clinical manifestations of hypothyroidismwhich is completely reversed by appropriate thyroid hormone replacement, is called catchupgrowth. The objective of this report is to determine the longitudinal growth of a girl withprolonged hypothyroidism due to Hashimoto’s thyroiditis complicated by precocious puberty.A 9-year-and-6-month-old girl presented with vaginal bleeding, growth failure and the typicalphysical signs of hypothyroidism due to Hashimoto’s thyroiditis. She received Eltroxinreplacement. The height has gained a total of 33 cm during 2 years and 6 months oftreatment without additional treatment by GnRHa or any combination of GH and GnRHa. Therecent age is 12 years, and her height is 145 cm which is within the target range. A patientwith long-standing hypothyroidism, complicated with precocious puberty, has the potential tocatch up with their height close to their genetic potential after thyroid hormone replacementalone.


Faculty of Medicine, Chulalongkorn University

First Page


Last Page