Characteristics of one Escherichia coli strain isolated from the sick red panda excreting mucus-like faeces

Authors

Dongjie Cai, College of Veterinary Medicine, Sichuan Agricultural UniversityFollow
Lanjing Ma, College of Veterinary Medicine, Sichuan Agricultural University
Xingxin Fu, The Second Affiliated Hospital of Chongqing Medical University
Bin Tian, Institute of Preventive Veterinary Medicine, Sichuan Agricultural University
David Ranucci, Department of Veterinary, University of Perugia

Abstract

The purpose of this study is to explore the main pathogens that caused one red panda to excrete mucus-containing faeces continuously. The anal swabs of sick red panda were collected for bacterial isolation, biochemical analysis, 16SrRNA sequencing identification, antimicrobial susceptibility testing, and research on pathogenicity in Mice. An Escherichia coli (E. coli) strain was isolated and determined. This strain was resistant to ampicillin, penicillin G, ceftiofur, and highly sensitive to levofloxacin, imipenem, azithromycin, kanamycin, and compound sulfamethoxazole. All mice died within 8-14 hours after injected intraperitoneally with 6×10⁸ CFU/mL E. coli. Histopathology showed that the lungs, livers, kidneys, and spleens of mice killed by E. coli showed different degrees of congestion and hemorrhage. The E. coli isolated from the red panda is multidrug-resistant and highly pathogenic for mice. This study can provide references for drug use and enhance understanding of E. coli-induced diarrhea in red pandas.

DOI

10.56808/2985-1130.3808

First Page

1

Last Page

6

Recommended Citation

Cai, Dongjie; Ma, Lanjing; Fu, Xingxin; Tian, Bin; and Ranucci, David (2026) "Characteristics of one Escherichia coli strain isolated from the sick red panda excreting mucus-like faeces," The Thai Journal of Veterinary Medicine: Vol. 56: Iss. 1, Article 15.
DOI: https://doi.org/10.56808/2985-1130.3808
Available at: https://digital.car.chula.ac.th/tjvm/vol56/iss1/15