Seroprevalence of Lawsonia intracellularis Antibodies among Large-scale Swine Farming Systems in Thailand

Authors

Thanh Che Nguyen, The International Graduated Program of Veterinary Science and Technology (VST), Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow
Chairani Ridha Maghfira, The International Graduated Program of Veterinary Science and Technology (VST), Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow
Nathaya Young, Boehringer Ingelheim Animal Health (Thailand) Limited, Bangkok 10310, ThailandFollow
Kanokwan Samatiwat, Boehringer Ingelheim Animal Health (Thailand) Limited, Bangkok 10310, ThailandFollow
Chaiyan Kaewpaluk, CPF (Thailand) Public Company Limited, Bangkok 10120, ThailandFollow
Apisak Laothanakit, CPF (Thailand) Public Company Limited, Bangkok 10120, ThailandFollow
Pawarisa Mungprasittichai, CPF (Thailand) Public Company Limited, Bangkok 10120, ThailandFollow
Roongroje Thanawongnuwech, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow
Yaowalak Panyasing, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow

Abstract

Gastrointestinal infectious diseases caused by bacteria have been a major problem in the swine industry, including Thailand. Porcine proliferative enteropathy (PPE), also known as porcine ileitis, is an enteric infectious disease caused by Lawsonia intracellularis – an obligate intracellular bacterium. PPE has been an economic threat to the global pork production system due to various types of diarrheas. Serological diagnosis can be applied to the seroprevalence of pathogen-antibodies and the timing of L. intracellularis infection when introduced to the herd. This present study showed the current serological status and the seroprevalence of antibodies against L. intracellularis in large-scale Thai swine herds using a commercial blocking enzyme-linked immunosorbent assay (ELISA). A total of 1,234 serums were sampled from 24 non-vaccinated commercial pig farms across Thailand as part of a monitoring program. The converted-herd seroprevalence was obtained in a total of 20 out of 24 herds sampled, and the within-herd seroprevalence was 51.0% (45.5-56.6%); older animals exhibiting higher seropositivity (93.8%, 95% CI: 80.5-100% and 100%, 95% CI: 100-100% in finishers and breeding pigs, respectively). Furthermore, the intensive-larger farms located in Northern Thailand manifested a 100% (95% CI: 100-100%) seropositive incidence as the highest frequency of Lawsonia-antibodies, followed by the Western (84.2%, 95% CI: 61.5-100%) and Eastern (69.1%, 95% CI: 56.4-81.0%) areas. There was a significant difference in the within-herd prevalence between site production systems (P < 0.001). Finally, in the absence of the L. intracellularis vaccine, porcine ileitis seroprevalence in large commercial swine herds in Thailand was prevailing.

DOI

10.56808/2985-1130.3530

First Page

481

Last Page

486

Recommended Citation

Nguyen, Thanh Che; Maghfira, Chairani Ridha; Young, Nathaya; Samatiwat, Kanokwan; Kaewpaluk, Chaiyan; Laothanakit, Apisak; Mungprasittichai, Pawarisa; Thanawongnuwech, Roongroje; and Panyasing, Yaowalak (2024) "Seroprevalence of Lawsonia intracellularis Antibodies among Large-scale Swine Farming Systems in Thailand," The Thai Journal of Veterinary Medicine: Vol. 53: Iss. 4, Article 5.
DOI: https://doi.org/10.56808/2985-1130.3530
Available at: https://digital.car.chula.ac.th/tjvm/vol53/iss4/5