Oxygenated dressing quickens skin wound healing of Bama miniature pigs

Authors

Yingqiu Wang
Limin Qiao
Hong An
Zhenhao Zhang
Yan Zheng
Chang Chen
Jingrui Zhang
Xiangguo Wang

Abstract

Oxygen is a vital factor in the process of wound healing and is involved in collagen synthesis, synthesis and the release of growth factors, angiogenesis and epidermal cell contraction. Hence, local oxygen control of wounds plays an important role in skin wound healing. Herein, we developed a novel oxygenated dressing for the treatment of skin wound healing in Bama miniature pigs. The oxygenated dressing was mainly composed of potassium iodide, glucose, glucose oxidase, polyvinyl alcohol, polypropylene, polyvinylpyrrolidone and water. The oxygenated dressing significantly quickens the healing of full-thickness skin wounds in Bama miniature pigs and promotes the proliferation of epidermal cells, basal and spinous cells, dermal vascular endothelial cells and fibroblasts, and then promote the benign healing of wounds.

DOI

10.56808/2985-1130.3228

First Page

377

Last Page

383

Recommended Citation

Wang, Yingqiu; Qiao, Limin; An, Hong; Zhang, Zhenhao; Zheng, Yan; Chen, Chang; Zhang, Jingrui; and Wang, Xiangguo (2022) "Oxygenated dressing quickens skin wound healing of Bama miniature pigs," The Thai Journal of Veterinary Medicine: Vol. 52: Iss. 2, Article 18.
DOI: https://doi.org/10.56808/2985-1130.3228
Available at: https://digital.car.chula.ac.th/tjvm/vol52/iss2/18