This study aimed to investigate, using magnetic resonance imaging, whether continuous hypertonic saline (HSS) infusion induces a superior vasodilating effect on the encephalic vessels compared to bolus infusion in dogs. The relative cross-sectional area of superior sagittal sinus increased to 1.96±0.09 and 1.69±0.31 times of the pre-value in the continuous and bolus groups, respectively, at t=30 min (p<0.001). However, the relative cross-sectional area of superior sagittal sinus was larger in the continuous group than that in the bolus group (p<0.001). The results suggest that continuous infusion of HSS might be superior to bolus infusion in inducing vasodilatation of the encephalic circulation.
Faculty of Veterinary Science, Chulalongkorn University
Murakami, Yoshiki; TSUKANO, Kenji; HIRATA, Haruyuki; KOIE, Hiroshi; and SUZUKI, Kazuyuki
"Optimal infusion rate of hypertonic saline to encephalic vessel vasodilatation using magnetic resonance imaging in normovolemic dogs,"
The Thai Journal of Veterinary Medicine: Vol. 52:
2, Article 16.
Available at: https://digital.car.chula.ac.th/tjvm/vol52/iss2/16