Optimal infusion rate of hypertonic saline to encephalic vessel vasodilatation using magnetic resonance imaging in normovolemic dogs

Authors

Yoshiki Murakami
Kenji TSUKANO
Haruyuki HIRATA
Hiroshi KOIE
Kazuyuki SUZUKI

Abstract

This study aimed to investigate, using magnetic resonance imaging, whether continuous hypertonic saline (HSS) infusion induces a superior vasodilating effect on the encephalic vessels compared to bolus infusion in dogs. The relative cross-sectional area of superior sagittal sinus increased to 1.96±0.09 and 1.69±0.31 times of the pre-value in the continuous and bolus groups, respectively, at t=30 min (p<0.001). However, the relative cross-sectional area of superior sagittal sinus was larger in the continuous group than that in the bolus group (p<0.001). The results suggest that continuous infusion of HSS might be superior to bolus infusion in inducing vasodilatation of the encephalic circulation.

DOI

10.56808/2985-1130.3226

First Page

369

Last Page

372

Recommended Citation

Murakami, Yoshiki; TSUKANO, Kenji; HIRATA, Haruyuki; KOIE, Hiroshi; and SUZUKI, Kazuyuki (2022) "Optimal infusion rate of hypertonic saline to encephalic vessel vasodilatation using magnetic resonance imaging in normovolemic dogs," The Thai Journal of Veterinary Medicine: Vol. 52: Iss. 2, Article 16.
DOI: https://doi.org/10.56808/2985-1130.3226
Available at: https://digital.car.chula.ac.th/tjvm/vol52/iss2/16