Multidrug resistant Escherichia coli Harboring Extendedspectrum β-Lactamase-encoding genes isolated from clinically healthy pigs

Authors

Khin Khin Lay
Haidee E. Torio
Asinamai Athliamai Bitrus
Wanida Mala
Nuananong Sinwat
Rungtip Chuanchuen

Abstract

A total of 292 E. coli isolates obtained from fecal samples from pigs in Central (n = 103) and Northeastern (n = 189) provinces of Thailand were included in this study. Eighty-six E. coli isolates were phenotypically confirmed to be β- lactamases producers and screened for the presence of β-lactamase genes. The CTX-M family was most frequently identified (90.7%). The blaCTX-M-15 gene belonging to CTX-M group I (59.3%) was the most predominantly identified CTX-M genotype followed by blaCTX-M-14 (31.4%) and blaCTX-M-4 (25.6%). The blaTEM-1 gene was prevalent (75.6%). The blaCTX-M-4 and blaCTX-M-14 genes were located on conjugative plasmid. The results highlighted healthy pigs as reservoirs of ESBL-producing E. coli carrying ESBL genes that could be horizontally transferred.

DOI

10.56808/2985-1130.3122

First Page

303

Last Page

310

Recommended Citation

Lay, Khin Khin; Torio, Haidee E.; Bitrus, Asinamai Athliamai; Mala, Wanida; Sinwat, Nuananong; and Chuanchuen, Rungtip (2021) "Multidrug resistant Escherichia coli Harboring Extendedspectrum β-Lactamase-encoding genes isolated from clinically healthy pigs," The Thai Journal of Veterinary Medicine: Vol. 51: Iss. 2, Article 13.
DOI: https://doi.org/10.56808/2985-1130.3122
Available at: https://digital.car.chula.ac.th/tjvm/vol51/iss2/13