The origin of dogs came from the limited number of founders leading to inbreeding or genetic diseasewithin or among breeds. Thai Ridgeback (TR) and Bangkaew (BK) dogs were the only native dog breeds that webelieved to originate in Thailand. The study of genetic variability in Thai dogs (39 Thai Ridgeback dogs, 82 Bangkaewdogs) was defined by using 12 microsatellite markers. These DNA markers were highly informative and distributedthrough the canine genome. The result from these markers revealed the higher number of alleles, observedheterozygosity (Ho), expected heterozygosity (He) and polymorphic information content (PIC) in TR and BK dogs.The average Ho, He and PIC were 0.72, 0.77, 0.73 in Bangkaew and 0.81, 0.78, 0.75 in Thai Ridgeback dogs. Theaverage inbreeding coefficient was 0.072 and -0.019 in Bangkaew and Thai Ridgeback dogs, respectively. The low andnegative inbreeding coefficient values revealed no inbreeding problem especially in Thai Ridgeback dog. Theinformation generated in this study could be used for further genetic study in Thai dogs and to investigate thepopulation structure in these dog breeds.
Faculty of Veterinary Science, Chulalongkorn University
Phavaphutanon, Janjira and Laopiem, Sudtisa
"Evaluation of Microsatellite Polymorphism and Genetic Variability in Thai Ridgeback and Bangkaew Dogs,"
The Thai Journal of Veterinary Medicine: Vol. 41:
3, Article 3.
Available at: https://digital.car.chula.ac.th/tjvm/vol41/iss3/3