Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine

Authors

Chatchai Sarachai
Jiroj Sasipreeyajan
Niwat Chansiripornchai

Abstract

Avian influenza virus (AIV) subtype H5N1 is known as a highly pathogenic agent for man and various kinds of animals, especially avian species. Herein, AIV H5N1 was inactivated by binary ethylenimine (BEI), an aziridine compound, produced from 2-bromoethylamine hydrobromide. BEI was used at concentrations of 0.001 and 0.01 M for AIV inactivation. At the lower concentration (0.001 M), AIV could be inactivated within 24 hr. At the higher concentration (0.01 M), AIV could be inactivated within 6 hr. After inactivation, no hemagglutination activity had been found meaning that AIV had been completely inactivated.

DOI

10.56808/2985-1130.2205

First Page

41

Last Page

46

Recommended Citation

Sarachai, Chatchai; Sasipreeyajan, Jiroj; and Chansiripornchai, Niwat (2010) "Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine," The Thai Journal of Veterinary Medicine: Vol. 40: Iss. 1, Article 4.
DOI: https://doi.org/10.56808/2985-1130.2205
Available at: https://digital.car.chula.ac.th/tjvm/vol40/iss1/4