"Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine" by Chatchai Sarachai, Jiroj Sasipreeyajan et al.

The Thai Journal of Veterinary Medicine

Article Title

Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine

Authors

Chatchai Sarachai
Jiroj Sasipreeyajan
Niwat Chansiripornchai

Abstract

Avian influenza virus (AIV) subtype H5N1 is known as a highly pathogenic agent for man and various kinds of animals, especially avian species. Herein, AIV H5N1 was inactivated by binary ethylenimine (BEI), an aziridine compound, produced from 2-bromoethylamine hydrobromide. BEI was used at concentrations of 0.001 and 0.01 M for AIV inactivation. At the lower concentration (0.001 M), AIV could be inactivated within 24 hr. At the higher concentration (0.01 M), AIV could be inactivated within 6 hr. After inactivation, no hemagglutination activity had been found meaning that AIV had been completely inactivated.

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Recommended Citation

Sarachai, Chatchai; Sasipreeyajan, Jiroj; and Chansiripornchai, Niwat (2010) "Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine," The Thai Journal of Veterinary Medicine: Vol. 40: Iss. 1, Article 4.
DOI: https://doi.org/10.56808/2985-1130.2205
Available at: https://digital.car.chula.ac.th/tjvm/vol40/iss1/4

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