The Thai Journal of Veterinary Medicine
Abstract
Avian influenza virus (AIV) subtype H5N1 is known as a highly pathogenic agent for man and various kinds of animals, especially avian species. Herein, AIV H5N1 was inactivated by binary ethylenimine (BEI), an aziridine compound, produced from 2-bromoethylamine hydrobromide. BEI was used at concentrations of 0.001 and 0.01 M for AIV inactivation. At the lower concentration (0.001 M), AIV could be inactivated within 24 hr. At the higher concentration (0.01 M), AIV could be inactivated within 6 hr. After inactivation, no hemagglutination activity had been found meaning that AIV had been completely inactivated.
DOI
10.56808/2985-1130.2205
First Page
41
Last Page
46
Recommended Citation
Sarachai, Chatchai; Sasipreeyajan, Jiroj; and Chansiripornchai, Niwat
(2010)
"Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine,"
The Thai Journal of Veterinary Medicine: Vol. 40:
Iss.
1, Article 4.
DOI: https://doi.org/10.56808/2985-1130.2205
Available at:
https://digital.car.chula.ac.th/tjvm/vol40/iss1/4