The Thai Journal of Veterinary Medicine
Abstract
Avian influenza virus (AIV) subtype H5N1 is known as a highly pathogenic agent for man and various kinds of animals, especially avian species. Herein, AIV H5N1 was inactivated by binary ethylenimine (BEI), an aziridine compound, produced from 2-bromoethylamine hydrobromide. BEI was used at concentrations of 0.001 and 0.01 M for AIV inactivation. At the lower concentration (0.001 M), AIV could be inactivated within 24 hr. At the higher concentration (0.01 M), AIV could be inactivated within 6 hr. After inactivation, no hemagglutination activity had been found meaning that AIV had been completely inactivated.
Publisher
Faculty of Veterinary Science, Chulalongkorn University
First Page
41
Last Page
46
Recommended Citation
Sarachai, Chatchai; Sasipreeyajan, Jiroj; and Chansiripornchai, Niwat
(2010)
"Avian Influenza Virus (H5N1) Inactivation by Binary Ethylenimine,"
The Thai Journal of Veterinary Medicine: Vol. 40:
Iss.
1, Article 4.
Available at:
https://digital.car.chula.ac.th/tjvm/vol40/iss1/4