PUPPIES ANTIBODY TITRE RESPONSE TO CANINE DISTEMPER VIRUS BEFORE AND AFTER VACCINATION WITH A CDV-COMBINED VACCINES

Authors

Woraporn Sukhumavasi
Boonlert Leephong
Silasak Kaewmaneerat
Suwit Gumtrontip
Monkon Trisiriroj
Pravina Kitikoon
Sumittra Watanodorn
Kanisak Oraveerakul

Abstract

Puppies antibody titer response to Canine Distemper virus (CDV) before and after vaccination with a CDV-combined vaccine was studied using a serum neutralization test (SN). A total of 201 samples were obtained from puppies at the Small Animal Hospital, Faculty of Veterinary Science, Chulalongkorn University. The result showed that 100%(82/82) of the puppies, before vaccination, had no detectable SN titre (CDV SN-titer <2). Puppies 14 days after the first and second vaccination had a log2 (geometric mean titer, GMT) of 5.2 and 7.8. A group of 20 puppies in which the antibody response was followed after vaccination for a period of time showed the comparable results (log2 [GMT] = 5.3 and 8.5, respectively). There was no difference in the CDV SN-titers among puppies of different ages at vaccination, nor those with a vaccination history for their mothers (p>0.05).

DOI

10.56808/2985-1130.1834

First Page

13

Last Page

23

Recommended Citation

Sukhumavasi, Woraporn; Leephong, Boonlert; Kaewmaneerat, Silasak; Gumtrontip, Suwit; Trisiriroj, Monkon; Kitikoon, Pravina; Watanodorn, Sumittra; and Oraveerakul, Kanisak (2000) "PUPPIES ANTIBODY TITRE RESPONSE TO CANINE DISTEMPER VIRUS BEFORE AND AFTER VACCINATION WITH A CDV-COMBINED VACCINES," The Thai Journal of Veterinary Medicine: Vol. 30: Iss. 4, Article 1.
DOI: https://doi.org/10.56808/2985-1130.1834
Available at: https://digital.car.chula.ac.th/tjvm/vol30/iss4/1