The Thai Journal of Veterinary Medicine


A urinary bladder mass was diagnosed in a 14-year-old uncastrated male mixed breed dog presented to the Small Animal Teaching Hospital, Faculty of Veterinary Science, Chulalongkorn University. The dog had periodic hematuria which had been present for eight months without any abnormalities on complete blood count and all other blood chemistry. Radiographic examination revealed a prostate gland enlargement with evidence of irregular thickening of the urinary bladder mucosa without any cystic calculi. Antibiotics and hemostatic drugs were given and hematuria ceased periodically. With a history of concurrent hematuria and an elevation of both blood urea nitrogen (109 mg%) and creatinine (3.6 mg%), the urinary cytology was performed. The urinalysis showed large numbers of pleomorphic epithelial cells with prominent nucleoli and dark staining nuclear membranes. Some were binucleated and multinucleated cells. These features suggested that transitional cell carcinoma was present in the urinary tract. Pneumocystography, double contrast cystography and ultrasonography were also performed and confirmed that the dog had neoplasia at the cranioventral part of urinary bladder. The dog died a few weeks later and necropsy was then performed. The results of histopathology revealed that the tumor was a transitional cell carcinoma.

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