The Thai Journal of Veterinary Medicine


The efficacy of flumequine was studied both in vitro and in vivo. The MIC was 0.5 ug/ml to 17 strains of A. hydrophila and 23 strains of V. anguillarum isolated from affected fishes and shrimps in Thailand. Sodium chloride (Nacl) has no effect on flumequine in inhibiting the growth of these bacterias. The mortality of shrimp (P. monodon) and seabass (L. calcarifer) was reduced at the dosage of 5 ppm, 10 ppm and 20 ppm when flumequine was administered every day or every 2 day. This drug should be one of the drug of choice in treatment of bacterial infection in aquatic animals.

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