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The Thai Journal of Veterinary Medicine

Abstract

Anthelmintic activity of single oral doses of oxfendazole at the rates of 2.5 and 5 milligrams per kilogram of body weight were determined by the Field trial method against gastrointestinal helminths in 30 calves. Oxfendazole at the rate of 2.5 milligrams per kilogram was highly effective (94.9 to 100 per cent) in reducing Bunostomum, Mecistocirrus digitatus, Haemonchus, Oesophagostomum, Trichostrongylus, Cooperia, Charbertia and Moniezia benedeni eggs from the first week to the sixth week posttreatment. Oxfendazole was less effective (75.2 to 86.4 percent) in reducing Strongyloides eggs from the first week to the eight week posttreatment. The drug was not effective in reducing Neoascaris vitulorum eggs. Oxfendazole at the rate of 5 milligrams per kilogram was highly effective (100 per cent) in reducing Bunostomum, M. digitatus, Haemonchus, Oesophagostomum, Trichostrongylus, Cooperia, Charbertia and M. benedeni eggs from the first week to the sixth week posttreatment. Oxfendazole was less effective (76.6 to 88.7 percent) in reducing Strongyloides eggs from the first week to the eight week posttreatment. The drug was not effective in reducing N. vitulorum eggs. Average daily weight gain was 0.50 and 0.52 kilogram in the oxfendazole treated calves at 2.5 and 5 milligrams per kilogram respectively, but it was only 0.25 kilogram in the untreated calves.

Publisher

Faculty of Veterinary Science, Chulalongkorn University

First Page

174

Last Page

186

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