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The Thai Journal of Veterinary Medicine

Abstract

Anthelmintic activity of single oral doses of febantel at the dose rates of 5, 10, and 20 milligrams per kilogram of body weight were determined by the field trials against nematodes in pigs. Febantel at a dose rate of 5 milligram per kilogram was highly effective (100 per cent) in reducing Ascaris suum and Oesophagostomum spp. eggs since the first week to the last week posttreatment. Febantel at a dose rate of 10 milligrams per kilogram was highly effective (100 per cent) in reducing A. suum eggs, but it was less effective (59.0 to 81.6 per cent) in reducing Strongyloides ransomi eggs. Febantel at a dose rate of 20 milligrams per kilogram was highly effective (100 per cent) in reducing S. ransomi and Trichuris suis eggs since the first week to the last week post-treatment. Average weight gain in the febantel-treated pigs was more than that in the untreated pigs throughout the experiment. Average daily weight gain in the febantel-treated pigs was 0.35 kilogram, but it was only 0.27 kilogram in the untreated pigs. Febantel at a dose rate of 5 milligrams per kilogram had no adverse effect on fertility, parturition or the mewborn. Febantel at a dose rate of 200 milligrams per kilogram or forty-fold overdosage had no effect on the health of the pigs.

First Page

193

Last Page

207

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