Effect of Zn addition on sol-gel derived apatite/wollastonite glass-ceramics scaffolds

Authors

S. Tubsungneon Rattanachan
N. Srakaew
R. Pethnin
N. Suppakarn

Publication Date

2012-12-01

Abstract

Bioactive glasses and glass-ceramics consisting of CaO-MgO-P2O5-SiO2 system have been shown to be bioactive, resorbable and to exhibit appropriate mechanical properties for bone tissue engineering applications. Bioactive glass-ceramics scaffolds consisting of zinc doped-apatite/wollastonite (AW) glassceramics were prepared by coating polyurethane foams with sol-gel derived glass gels. Density and compressive strength of the scaffolds decreased with increased in zinc contents. In vitro bioactivity of Zndoped AW glass-ceramics in a simulated body fluid (SBF) showed the formation of apatite layer on the surface within 7 days of soaking. However, increasing Zn addition increased the chemical durability of the AW glass-ceramics, resulting in a decrease in the rate of apatite formation in a simulated body fluid. With observation by SEM technique microstructure of pores showed interconnected macropores in the range of 300-500 μm as depended on the type of sponge. Average pore size increased with increasing the zinc additions. Macropores and interconnect size can be tailored by controlling the zinc concentrations.

First Page

61

Last Page

65

Recommended Citation

Rattanachan, S. Tubsungneon; Srakaew, N.; Pethnin, R.; and Suppakarn, N. (2012) "Effect of Zn addition on sol-gel derived apatite/wollastonite glass-ceramics scaffolds," Journal of Metals, Materials and Minerals: Vol. 22: No. 2, Article 10.
Available at: https://digital.car.chula.ac.th/jmmm/vol22/iss2/10