Journal of Metals, Materials and Minerals

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Mesoporous silica was produced by sol-gel technique using rice husk ash as a silica source which was applied in the drug delivery system. The drug releasing behavior was studied in phosphate buffer using indigo carmine as a drug model. The textural properties of mesoporous silica were characterized and considered with the result of the releasing study. The pore volume and silanol group on the surface of mesoporous silica affected the releasing behavior. The larger pore volume could contain the larger amount of drug which showed fast release. The effect of the silanol group presented an interaction between the drug molecule and silanol group resulting in slower releasing.

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