Administration of the semisynthetic diet containing aflatoxin B1 at the level of 20 ppm for 4 wks induced testicular degeneration in the male Buffalo strain rats. Various degrees of seminiferous epithelial degeneration were observed and described by light microscopy. However, testes of rats that survived until the end of the experiment (32 wks) showed only slight thickening of the basement membrane and a decrease in diameter of the seminiferous tubules. This observations suggested that aflatoxin B1 had only a transient toxic effect on rat testes.
Angsubhakorn, Subhkij; Bhamarapravati, Natth; Romruen, Kanda; Prangprakma, Virat; Sahaphong, Somphong; and Thamavit, Witaya
"Testicular Degeneration Following Aflatoxin B1 Administration in Rats,"
The Thai Journal of Veterinary Medicine: Vol. 8:
2, Article 1.
Available at: https://digital.car.chula.ac.th/tjvm/vol8/iss2/1