Impact of colostrum lactose concentration in relation to metabolomic profiles on kid growth performance of Black Bengal goats

Authors

Tien Thi Phuong Vo, Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow
Chollada Buranakarl, Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Henri Dunant Rd., Pathumwan, Bangkok 10330, ThailandFollow
Sumonwan Chamsuwan, Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow
Sumpun Thammacharoen, Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandFollow
Morakot Nuntapaitoon, Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, and Multi-Omics for Functional Products in Food, Cosmetics and Animals Research Unit, Chulalongkorn University, Bangkok, 10330, ThailandFollow
Sarn Settachaimongkon, Department of Food Technology, and Omics Sciences and Bioinformatics Center, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.Follow

Abstract

Colostrum composition, including lactose concentration in relation to metabolomic profiles on kids’ growth performance of Black Bengal goats, has not yet been elucidated. Macronutrients, including lactose and metabolomic profiles, were determined in 37 colostrum samples using MilkoScan and 1H-nuclear magnetic resonance technique, respectively. Kids’ growth performance, including birth weight, average daily gain at 0–4 weeks (ADG0-4W), 4–8 weeks (ADG4-8W), and wean weight were determined. A total of 51 metabolites were detected in the colostrum. From the general linear model for univariate analysis, kids born from multiple litter sizes showed lower ADG during the first month postpartum (P = 0.004). The ADG0-4W was correlated positively with lactose (r = 0.434, P < 0.001), betaine (r = 0.263, P < 0.05), glycine (r = 0.303, P < 0.05), and trimethylamine N-oxide (r = 0.372, P < 0.01) but negatively with most metabolites. By using a generalized linear mixed model procedure when kid growth performances were regarded as dependent variables, and the damID was considered as a random effect with birth weight, parity number, and litter size as covariates, kids consumed colostrum with high lactose (P < 0.001) but lower protein, fumarate, malonate, glucose, myo-inositol, vitamin B2, and vitamin B7 (P < 0.05) had higher ADG0-4W. Therefore, growth performance 1 month postpartum was enhanced in kids consuming high lactose with low metabolite contents, which reflects not only the lactose is the main source of energy but also its possible role on the osmotic water-pulling effect on colostrum yield.

DOI

10.56808/2985-1130.3833

First Page

1

Last Page

10

Recommended Citation

Vo, Tien Thi Phuong; Buranakarl, Chollada; Chamsuwan, Sumonwan; Thammacharoen, Sumpun; Nuntapaitoon, Morakot; and Settachaimongkon, Sarn (2025) "Impact of colostrum lactose concentration in relation to metabolomic profiles on kid growth performance of Black Bengal goats," The Thai Journal of Veterinary Medicine: Vol. 55: Iss. 2, Article 2.
DOI: https://doi.org/10.56808/2985-1130.3833
Available at: https://digital.car.chula.ac.th/tjvm/vol55/iss2/2