Acinetobacter baumanniihas emerged as a nosocomial pathogen and considered as a major cause of hospital acquired infections. While A. baumanniiin humans have been extensively studied in various situations, the study of A. baumanniiin companion animals is still limited. The aim of this study was to examine the presence and antimicrobial resistance profile of A. baumanniiisolates from companion rabbits. A total of 17 nasal swab from rabbit carcasses were obtained. A. baumanniiwas detected in 23.53% (4/17) of the samples and all the isolates exhibited resistance to chloramphenicol, erythromycin, spectinomycin and trimethoprim. Fifty percent of the isolates (2/4) were multidrug resistance (MDR) A. baumannii(ABR601 and ABR604) and produced all the Ade multidrug efflux tested including AdeABC, AdeFGH and AdeIJK. The other 2 isolates, including ABR602 and ABR603, demonstrated different expression profile of the Ade systems i.e. AdeIJK and AdeFGH-AdeIJK, respectively. Of all the isolates, ABR604 and ABR601 were resistant to 12 and 10 out of the 15 antimicrobials tested, respectively. This study indicates the presence of MDR A. baumannii in pets other than dogs and cats and highlights the possible role of these animals as reserviors for the spread of MDR A. baumanniito humans, animals and environment.
Faculty of Veterinary Science, Chulalongkorn University
Pagdepanichkit, Sirawit and Chuanchuen, Rungtip
"Rabbit as a reservoir of multidrug-resistant Acinetobacter baumanniiexpressing the Ade multidrug efflux pumps,"
The Thai Journal of Veterinary Medicine: Vol. 50:
4, Article 11.
Available at: https://digital.car.chula.ac.th/tjvm/vol50/iss4/11