The Thai Journal of Veterinary Medicine


The study aims to investigate the efficacy of piroline and antibiotics in the treatment of bovine mastitiscaused by Streptococcus uberis (S. uberis) and Escherichia coli (E. coli) during dry-milk period. 1880 cows in dry-milkperiod were divided into 4 groups and treated with penicillin G, ammonia benzyl penicillin, ceftiofur and piroline,respectively. The efficacy of each medicine in treating mastitis caused by E. coli intramammary infection (E. coli IMI)was followed: 31.2% for penicillin G, 36.9% for ammonia benzyl penicillin, 61.3% for ceftiofur, and 64.4% for Piroline.For those caused by S. uberis intramammary infection (S. uberis IMI), the efficacy of ceftiofur was 90% and pirolinewas 94.4%. The results indicated that piroline was more effective than the other three in treating the disease. Thefollowing analysis on milk samples demonstrated that there was no piroline residue in those treated cows’ milk.Based on these data, it can be predicted that piroline will have a bright future in treating cow intramammary mastitis.

First Page


Last Page