Porcine small intestinal submucosa (PSIS) was used as a graft to repair 13 dogs with deep corneal ulceration. Eight cases had staphyloma and staphyloma associated with hyphema. Two cases had staphyloma associated with glaucoma. There was one case of each of descemetocoele, descemetocoele associated with glaucoma and rupture of the cornea. Ten dogs without glaucoma returned to normal vision (76.93%) with minimal anterior synechia and scarring. Three dogs with associated glaucoma became blind (23.07%). PSIS has been demonstrated to stimulate corneal healing without tissue rejection and is recommended to be used as a graft material to repair deep corneal ulcers in dogs.
Briksawan, Pasakorn; Wongaumnuaykul, Sunti; Tuntivanich, Pranee; Tuntivanich, Nalinee; and Sunthornvipat, Kumpanart
"THE USE OF PORCINE SMALL INTESTINAL SUBMUCOSA (PSIS) IN A CANINE DEEP CORNEAL ULCER,"
The Thai Journal of Veterinary Medicine: Vol. 33:
2, Article 1.
Available at: https://digital.car.chula.ac.th/tjvm/vol33/iss2/1