The Thai Journal of Veterinary Medicine
Abstract
The safety of trichlorfon at a therapeutic dose for ectoparasitic treatment in healthy carp (Cyprinus carpio) was evaluated by the measurement of serum cholinesterase (ChE) activity. Three groups of juvenile carp (70-80 g b.w., n =30 each) were bathed with 0.5 ppm trichlorfon 1, 2 or 3 times, respectively, at 5-day intervals. Serum ChE activity in each fish were compared pre and post-treatment. A significant post-treatment reduction of serum ChE activity (p < 0.05) was found in all groups, although they, resumed their pre-treatment levels 14 days after trichlorfon was withdrawn. All fish were clinically healthy throughout the experiment, suggesting, that the doses of trichlorfon applied in this study were safe.
Publisher
Faculty of Veterinary Science, Chulalongkorn University
First Page
45
Last Page
49
Recommended Citation
Pet-in, Rangsiwan; Thumma, Rujira; Nimittritip, Ubonrat; Wongtavatchai, Janenuj; and Chansiripornchai, Piyarat
(2003)
"SAFETY EVALUATION OF TRICHLORFON USED AT A THERAPEUTIC DOSE LEVEL FOR ECTOPARASITIC TREATMENT BY STUDYING SERUM CHOLINESTERASE ACTIVITY MEASUREMENTS IN CARP (CYPRINUS CARPIO),"
The Thai Journal of Veterinary Medicine: Vol. 33:
Iss.
1, Article 4.
Available at:
https://digital.car.chula.ac.th/tjvm/vol33/iss1/4