IMMUNOHISTOCHEMICAL DETECTION OF FELINE VIRAL RHINOTRACHEITIS IN A CAT

Authors

Nopadon Pirarat
Yumi Une
Yasuo Nomura

Abstract

A female, 10-month old, mixed breed cat showed clinical signs of severe dehydration, purulent nasal discharge, dyspnea, severe crepitating lung sounds and no response to antibiotic treatment. Upon necropsy, histopathology revealed severe, diffuse, fibrinopurulent pleuropneumonia and numerous, homogeneous, amphophilic, intranuclear inclusion bodies in the pulmonary alveolar macrophages, bronchial and alveolar epithelium and bronchial glandular epitheliums. Immunohistochemical studies using 3 different monoclonal, anti-Feline Herpesvirus type 1 antibodies, revealed immunoreactivity of viral antigen in the lung that was associated with the histopathological changes. Monoclonal, anti-glycoprotein B, antibody showed the strongest immunoreactivity.

DOI

10.56808/2985-1130.1863

First Page

41

Last Page

46

Recommended Citation

Pirarat, Nopadon; Une, Yumi; and Nomura, Yasuo (2001) "IMMUNOHISTOCHEMICAL DETECTION OF FELINE VIRAL RHINOTRACHEITIS IN A CAT," The Thai Journal of Veterinary Medicine: Vol. 31: Iss. 4, Article 4.
DOI: https://doi.org/10.56808/2985-1130.1863
Available at: https://digital.car.chula.ac.th/tjvm/vol31/iss4/4