Study on efficacy of inermectin against Gnathostoma spinigerum (Nematoda : Spiruroidea advanced third stage larva in rats)

Authors

J. Waikagul
S. Nuamtanong
M.T. Anantaphruti
S. Nithiuthai

Abstract

Gnathostomiasis is one of the fatal nematode infections which at present effective chemotherapy is unavailable. Recently, ivermectin has been reported to be highly effective against intestinal and tissue nematodes. The efficacy against advanced third stage larvae of G. spinigerum of ivermectin were tested in the white rats with a single dose or multidoses of 2 mg/kg. Worm reductions observed at week 20 after treatment were about 90 % in average but there was no cure rate.

DOI

10.56808/2985-1130.1573

First Page

91

Last Page

103

Recommended Citation

Waikagul, J.; Nuamtanong, S.; Anantaphruti, M.T.; and Nithiuthai, S. (1991) "Study on efficacy of inermectin against Gnathostoma spinigerum (Nematoda : Spiruroidea advanced third stage larva in rats)," The Thai Journal of Veterinary Medicine: Vol. 21: Iss. 2, Article 6.
DOI: https://doi.org/10.56808/2985-1130.1573
Available at: https://digital.car.chula.ac.th/tjvm/vol21/iss2/6