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The Thai Journal of Veterinary Medicine

Abstract

Anthelmintic activity of single doses of thiophanate at the rates of 70, 100, and 200 milligrams per kilogram of body weight were determined by the field trial against nematodes in 40 pigs. Thiophanate at a dose rate of 70 milligrams per kilogram was highly effective (90.2 to 98.4 percent) in reducing Ascaris suum and Strongyloides ransomi eggs from the first week to the twelth week posttreatment. The drug was 100 per cent effective in reducing Oesophagostomum spp. and Trichuris suis eggs throughout the twelve experimental weeks. Thiophanate at a dose rate of 100 milligrams per kilogram was highly effective (91.4 to 100 per cent) in reducing A. suum and S. ransomi eggs from the first week to the twelth week posttreatment. The drug was 100 percent effective in reducing Oesophagostomum spp. and T. suis eggs throughout the twelve experimental weeks.Thiophanate at a dose rate of 200 milligrams per kilogram was highly effective (94.3 to 100 percent) in reducing A. Suum and S. ransomi eggs from the first week to the twelth week. The drug was 100 percent effective in reducing Oesophagostomum spp. and T. suis eggs throughout the twelve experimental weeks. Thiophanate at a dose rate of 70 milligrams per kilogram had no effect on fertility, embryos or foetuses. Thiophanate was well tolerated by pigs when administered as a single doses up to 3000 milligrams per kilogram.

Publisher

Faculty of Veterinary Science, Chulalongkorn University

First Page

103

Last Page

109

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