The toxicity of nitroxynil administered subcutaneously was determined in Thai native and crossbred calves and yearling cattle. Maximum tolerated dosage was 50 milligrams per kilogram in calves and yearling cattle. Lethal dosage were 55 milligrams per kilogram in calves and yearling cattle. The toxic doses caused the animals death in 24 to 28 hours with clinical signs. At the dose rate of 10 milligrams per kilogram, nitroxynil had no effect on fertility, embryoes or foetuses. The drug could be administered repeatedly at 1 month interval to the pregnant cows up to 8 months of gestation period without affecting reproductive performance.
Faculty of Veterinary Science, Chulalongkorn University
"The Tixicity of Nitoxynil in Cattle,"
The Thai Journal of Veterinary Medicine: Vol. 13:
4, Article 3.
Available at: https://digital.car.chula.ac.th/tjvm/vol13/iss4/3