Virtual screening for novel 1-deoxy-d-xylulose-5-phosphate reductoisomerase inhibitors: A shape-based search approach

Authors

Prasan Tangyuenyongwatana
Wandee Gritsanapan

Abstract

A virtual screening study with ArgusLab 4.0.1 was performed on 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), the second enzyme in the methyl erythritol phosphate pathway in isoprenoids production which is present in malarial parasite Plasmodium .

Publisher

Faculty of Pharmaceutical Sciences, Chulalongkorn University

First Page

1

Last Page

5

Recommended Citation

Tangyuenyongwatana, Prasan and Gritsanapan, Wandee (2017) "Virtual screening for novel 1-deoxy-d-xylulose-5-phosphate reductoisomerase inhibitors: A shape-based search approach," The Thai Journal of Pharmaceutical Sciences: Vol. 41: Iss. 1, Article 1.
Available at: https://digital.car.chula.ac.th/tjps/vol41/iss1/1