Abstract
Background: Stroke is a leading cause of death among older adults with uncontrolled hypertension. However, most studies focus on stroke patients rather than those at risk. This study examined stroke risk levels in older adults with uncontrolled hypertension in Chiang Rai, Thailand, and explored their associations with multilevel factors using an ecological model.
Methods: A cross-sectional analytic study was conducted in a community of 238 individuals aged 60–69 years using multistage stratified random sampling. Data were collected through structured interviews and physical examinations (September-November 2023). The instruments were validated for reliability and met standard acceptance criteria. Binary logistic regression with adjusted odds ratio (AOR) was used to identify significant factors associated with a high risk of stroke.
Results: 84% of participants had a high 10-year risk of stroke. Eight factors were significantly associated with a high risk of stroke (p < 0.05), contributing to 45.3% of the risk. These factors included male gender, unemployment status, systolic blood pressure, body mass index, waist circumference exceeding the standard, number of cigarettes smoked daily, and perceived barriers to stroke prevention. Diastolic blood pressure was identified as a protective factor against stroke risk.
Conclusions: Significant factors associated with a high risk of stroke were individual variables. The risk could be minimized by engaging individuals in regular exercise, educating them about healthier food choices, motivating smoking cessation, and regularly monitoring blood pressure and salt intake during home visits by village health volunteers.
Keywords: Aging, Stroke, Hypertension, Health belief model, Social support, Thailand
Recommended Citation
Tanapek S, Benjakul S, Kengganpanich M, Sillabutra J.
Identifying stroke risk and its association with multilevel factors among older people with uncontrolled hypertension in Chiang Rai, Thailand: a cross-sectional analytic study.
J Health Res.
2025;
39(2):-.
DOI: https://doi.org/10.56808/2586-940X.1132
References
[1] Ministry of Social Development and Human Security, Department of Older Persons. Situation of the Thai older persons 2022. Bangkok: Amarin Corporations; 2023 [cited 2023 Oct 10]. Available from: https://www.dop.go.th/download/knowledge/th1696238995-2521_0.pdf.
[2] Ministry of Interior. Number and proportion of population from registration. Bangkok: Ministry; 2023 [cited 2023 Nov 16]. Available from: https://stat.bora.dopa.go.th/stat/statnew/statMONTH/statmonth/#/view.
[3] World Health Organization [WHO]. Global health estimates 2019: disease burden by cause, age, sex, by country and by region, 2000-2019. Geneva: WHO; 2020 [cited 2023 Nov 16]. Available from: https://www.who.int/data/gho/data/themes/ mortality-and-global-health-estimates/global-healthestimates-leading-causes-of-dalys.
[4] Ministry of Public Health [MOPH]. Strategy and planning division. Public health statistics A.D.; 2021. Nonthaburi: MOPH;2022[cited 2023 Nov 16]. Available from: https://spd.moph.go.th/wp-content/uploads/2022/11/Hstatistic64.pdf.
[5] Ministry of Public Health [MOPH]. HDC report; Stroke morbidity rate. Nonthaburi: MOPH; 2024 [cited 2024 Feb 20]. Available from: https://hdcservice.moph.go.th/ hdc/reports/report.php?source=formated/ncd.php&cat_id= 6a1fdf282fd28180eed7d1cfe0155e11&id=3092c3c3250ae67155 f7e134680c4152#.
[6] Ministry of Public Health [MOPH]. HDC report; Case fatality rate of stroke. Nonthaburi: MOPH; 2024 [cited 2024 Feb 20]. Available from: https://hdcservice.moph.go.th/hdc/reports/ report.php?&cat_id=6a1fdf282fd28180eed7d1cfe0155e11&id= 9bf46fa15f85178a05b665ae986bd467#.
[7] Ministry of Public Health [MOPH]. Strategy and Planning Division. Number and death rate from 4 NCD diseases per 100,000 people, 2017e2021. Nonthaburi: MOPH; 2023 [cited 2023 Nov 16]. Available from: http://www.thaincd.com/2016/mission/documentsdetail.php?id=14480&tid=32&gid=1-020.
[8] Webb AJS, Werring DJ. New Insights Into Cerebrovascular Pathophysiology and Hypertension. Stroke 2022 Apr;53(4): 1054-64. https://doi.org/10.1161/STROKEAHA.121.035850.
[9] Syukriyah SRZMD, Al Fauzi A. Hypertension as a risk factor in stroke: an overview. WJARR 2024;21(1):2370-2. https://doi. org/10.30574/wjarr.2024.21.1.0204.
[10] Areechokchai D, Vijitsoonthornkul K, Pongpan S, Maeakhian S. Population attributable fraction of stroke risk factors in Thailand: Utilization of non-communicable disease surveillance systems. OSIR 2017;10(1):1-6. https://doi.org/10. 59096/osir.v10i1.263188.
[11] Saicamthon P, Tipsriraj S, Chaisaen K, Yingyong T, sugawong K. The effect of risk factors for cerebrovascular disease, Regional health 1, Thailand. Lanna Public Health 2016;12(2):44-53.
[12] Srithumsuk W, Kabayama M, Gondo Y, Masui Y, Akagi Y, Klinpudtan N, et al. The importance of stroke as a risk factor of cognitive decline in community dwelling older and oldest peoples: the SONIC study. BMC Geriatr 2020 Jan 22;20(1):24. https://doi.org/10.1186/s12877-020-1423-5.
[13] Wang H, Wu M, Tu Q, Li M. Risk factors for stroke in a population of central China: a cross-sectional study. Medicine (Baltim) 2022 Nov 18;101(46):e31946. https://doi.org/10.1097/MD.0000000000031946.
[14] Samuthpongtorn C, Jereerat T, Suwanwela NC, Samuthpongtorn C, Jereerat T, Suwanwela NC. Stroke risk factors, subtypes and outcome in elderly Thai patients. BMC Neurol 2021 Aug 20;21(1):322. https://doi.org/10.1186/s12883021-02353-y.
[15] Lin H, Wu Y, Wu J, Chen Q, Yu J, Lin Y. Prevalence of Hypertension and 10-Year Cardiovascular Disease Risk Among Older Adults Living in Quanzhou, A Coastal Region of Southeast China. Risk Manag Healthc Policy 2022 May 13;15: 1045-53. https://doi.org/10.2147/RMHP.S341148.
[16] Sazlina SG, Sooryanarayana R, Ho BK, Omar MA, Krishnapillai AD, Mohd Tohit N, et al. Cardiovascular disease risk factors among older people: Data from the National Health and Morbidity Survey 2015. PLoS One 2020 Oct 21;15(10):e0240826. https://doi.org/10.1371/journal.pone.0240826.
[17] Liu Q, Huang YJ, Zhao L, Wang W, Liu S, He GP, et al. Association between knowledge and risk for cardiovascular disease among older adults: A cross-sectional study in China. Int J Nurs Sci 2020 Mar 28;7(2):184-90. https://doi.org/10.1016/j.ijnss.2020.03.008.
[18] Markmee P, Kanthawee P, Thepaksorn P. An exploratory study of prevalence and associated factors of cardiovascular risk among elderly with hypertension in Chiang Rai Province. IJPHS 2021;3(2):1-12.
[19] Duque S, Fernandes L, Correia A, Calvinho I, Cardoso G, Pinto M, et al. Awareness of Stroke Risk Factors and Warning Signs and Attitude to Acute Stroke. Int Arch Med 2015;8. https://doi.org/10.3823/1794.
[20] Kingkaew N, Antadech T. Cardiovascular risk factors and 10year CV risk scores in adults aged 30-70 years old in Amnat Charoen Province, Thailand. Asia Pac J Sci Technol 2019; 24(4). APST-24.
[21] Arasean K, Kalampakorn S, Sillabutra J. Risk of cerebrovascular disease among bank officers at risk and risk factorsrelated. J Pub Health Nurse 2019;33(1):92-106 [ in Thai].
[22] Nagayoshi M, Everson-Rose SA, Iso H, Mosley Jr TH, Rose KM, Lutsey PL. Social network, social support, and risk of incident stroke: Atherosclerosis Risk in Communities study. Stroke 2014 Oct;45(10):2868-73. https://doi.org/10.1161/STROKEAHA.114.005815.
[23] Freak-Poli R, Phyo AZZ, Hu J, Barker SF. Are social isolation, lack of social support or loneliness risk factors for cardiovascular disease in Australia and New Zealand? A systematic review and meta-analysis. Health Promot J Austr 2022 Oct; 33(Suppl 1):278-315. https://doi.org/10.1002/hpja.592.
[24] Ministry of Social Development and Human Security. Department of Older Persons. Number of Thai elderly classified by province 2023. Bangkok: Ministry; 2023 [cited 2023 Nov 16]. Available from: https://www.dop.go.th/th/know/side/1/1/2449.
[25] McLeroy KR, Bibeau D, Steckler A, Glanz K. An ecological perspective on health promotion programs. Health Educ Q 1988 Winter;15(4):351-377. doi: 10.1177/109019818801500401.
[26] Glanz K, Rimer BK, Viswanath K. Health behavior: theory, research, and practice. San Francisco: John Wiley & Sons; 2015.
[27] House JS. Work stress and social support. MA: Addison Wesley; 1981.
[28] Aekplakorn W, editor. The 6th Thai national health examination survey 2019-2020. Bangkok: Auksorn Graphic and Design; 2021.
[29] Daniel WW. Biostatistics: a foundation for analysis in the health science. 10th ed. NJ: John Wiley and Sons; 2013.
[30] Mahidol University, Faculty of Medicine Ramathibodi Hospital. Thai CV risk score. Bangkok: Mahidol University; 2015 [cited 2023 Nov 16]. Available from: https://med.mahidol.ac.th/cardio_vascular_risk/thai_cv_risk_score/tcvrs_en. html#eegat3.
[31] World Health Organization [WHO]. The Asia-Pacific perspective: redefining obesity and its treatment. Geneva: WHO; 2000 [cited 2023 Nov16]. Available from: https://www.vepachedu.org/TSJ/BMI-Guidelines.pdf.
[32] World Health Organization [WHO]. Global recommendations on physical activity for health. Geneva: WHO; 2010 [cited 2023 Nov 16]. Available from: https://iris.who.int/ bitstream/handle/10665/44399/9789241599979_eng.pdf? sequence=1.
[33] Bloom BS. Handbook on formative and summative evaluation of student learning. New York: McGraw-Hill; 1971.
[34] Ponraj DGS, Gopikrishnan SK, Newtonraj A, Arokiaraj MC, Purty AJ, Nanda SK, et al. Cardiovascular risk using WHO-ISH chart among diabetes and hypertensive patients in a remote rural area of South India. J Fam Med Prim Care 2020 Aug 25;9(8):4145-50. https://doi.org/10.4103/jfmpc.jfmpc_538_20.
[35] Barker-Collo S, Bennett DA, Krishnamurthi RV, Parmar P, Feigin VL, Naghavi M, et al. Sex differences in stroke incidence, prevalence, mortality and disability-adjusted life years: results from the global burden of disease study 2013. Neuroepidemiology 2015;45(3):203-14. https://doi.org/10.1159/000441103.
[36] Park SE, So WY, Kang YS, Yang JH. Relationship between perceived stress, obesity, and hypertension in Korean adults and older adults. Healthcare (Basel) 2023 Aug 11;11(16):2271. https://doi.org/10.3390/healthcare11162271.
[37] Long GH, Cooper AJ, Wareham NJ, Griffin SJ, Simmons RK. Healthy behavior change and cardiovascular outcomes in newly diagnosed type 2 diabetic patients: a cohort analysis of the ADDITION-Cambridge study. Diabetes Care 2014 Jun; 37(6):1712-20. https://doi.org/10.2337/dc13-1731.
[38] Sobieraj P, Lewandowski J, Sinski M, Symonides B, Gaciong Z. Low diastolic blood pressure is not related to risk of first episode of stroke in a high-risk population: a secondary analysis of SPRINT. J Am Heart Assoc 2019 Feb 19; 8(4):e010811. https://doi.org/10.1161/JAHA.118.010811.
[39] Darsini D, Hamidah H, Notobroto HB, Cahyono EA. Health risks associated with high waist circumference: a systematic review. J Public Health Res 2020 Jul 2;9(2):1811. https://doi.org/10.4081/jphr.2020.1811.
[40] Benowitz NL, Burbank AD. Cardiovascular toxicity of nicotine: implications for electronic cigarette use. Trends Cardiovasc Med 2016 Aug;26(6):515-23. https://doi.org/10.1016/ j.tcm.2016.03.001.